1. iPSC generation from somatic cells

Induced pluripotent stem (iPS) cells are a type of pluripotent stem cell (PSC) that can be obtained by reprogramming somatic cells through artificial expression of key transcription factors under specific culture conditions. Variables that affect reprogramming include the delivery method, culture conditions and starting cell type. The choice of starting cell type is influenced by factors such as availability of donor tissue, invasiveness of sample collection procedures, genomic integrity, epigenetic memory and reprogramming efficiency. For efficient reprogramming, use our non-viral and non-integrating vector system , TeSR-based media , and small molecules.

2. Stem Cell Quality Control

By using culture assays, we functionally validate the ability of new or established human embryonic stem (ES) and induced pluripotent stem (iPS) cell lines to differentiate to the three germ layers: ectoderm, mesoderm, and endoderm. With specialized, complete media and monolayer-based protocols to perform parallel in vitro directed differentiation experiments for each germ layer, clearly and reproducibly establishing trilineage differentiation.

3. Human Stem Cell derived brain organoids

Human organoids are stem cell derived 3D structures, which allow in vitro study of a huge range of biological processes, development and human diseases and disorders, since they mimic several living tissue features. The novel technology of induction of brain organoids derived from human stem cells provides opportunities to study human brain development and associated disorders. In our facility we use suitable protocols and procedures to maintain dorsal, ventral and midbrain organoids for further studying.

4. Human Stem Cell derived neuronal & non-neuronal cells

We offer comprehensive services for the generation and characterization of human stem cell-derived neuronal and non-neuronal cells. Our expertise enables researchers to obtain high-quality, differentiated cell types that are essential for advancing studies in neuroscience, drug discovery, and regenerative medicine. Through meticulous characterization processes, we ensure that the cells meet specific functional and phenotypic criteria, providing a reliable foundation for experimental applications and therapeutic development.