The Biomedical Research Institute (BRI) at FORTH (Foundation for Research and Technology - Hellas) has a rich history of scientific advancement. Initially established in 1998 in Ioannina under the General Secretariat for Research and Technology (GSRT), BRI was an independent institute until 2012, when it became part of the Institute of Molecular Biology & Biotechnology (IMBB) at FORTH. However, in 2021, BRI was re-established as an independent institute following legislative changes, emphasizing its significance in biomedical research.

Currently, BRI hosts 18 research teams with over 140 members, focusing on areas such as cancer biology, stem cell biology, neurobiology, and biomedical technology. The institute plays a significant role in advancing research on regenerative medicine and tissue engineering. Its cutting-edge facilities include high-end microscopy units, some of which are unique in Greece.

The current director of BRI is Prof. Savvas Christoforidis, a professor at the Faculty of Medicine at the University of Ioannina, specializing in biological chemistry. His leadership marks a new phase of growth for BRI, with extensive research projects funded by national and European programs.

Prof. Theodore Fotsis served as the director of the Biomedical Research Institute (BRI) from December 2006 until February 2012. After the merger of BRI with the Institute of Molecular Biology & Biotechnology (IMBB), he became the head of the newly formed IMBB-BR division until August 2019. Dr. Fotsis is known for his contributions to biomedical research, particularly in the fields of vascular biology, angiogenesis and cancer biology. He was recently honoured as a distinguished member of FORTH and awarded the title of Emeritus Professor at the University of Ioannina.