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Maria Markou
Foundation for Research & Technology-Hellas
Biomedical Research Institute - BRI
University Campus of Ioannina
45 115 Ioannina, Greece
Phone : +30 26510 07816
Education and training
B.Sc
Dept of Biological Applications and Technology, University of Ioannina (2010-2015)
PhD
Laboratory of Biological Chemistry, Medical School-University of Ioannina (UOI) & Division of Biomedical Research of the Institute of Molecular Biology and Biotechnology Foundation for Research and Technology-Hellas (FORTH-IMBB), Ioannina. Project title: Molecular mechanisms of VEGF in vasculogenesis and applications in regenerative medicine (2016-present)
Work experience
1. Diploma thesis. Division of Biomedical Research of the Institute of Molecular Biology and Biotechnology Foundation for Research and Technology-Hellas (FORTH-IMBB), Ioannina. Project title: “Differentiation of vascular progenitor cells on scaffolds for the generation of vascular tissues in vitro” (11/2014-11/2015)
2. Fellowship for post-graduate studies of the second-cycle (PhD) in Greece from The State Scholarships Foundation, in the framework of the Operational Programme “Education and Life Long Learning”
3. Researcher in the project funded by the program "Siemens-Biology-Biophotonics”. ¨Differentiating hESCs / hiPSCs to cells of mesodermal origin. Study of basic molecular mechanisms and applications in Regenerative Medicine¨
Training
• Mesenchymal Stem Cell culture and identification with FACS analysis with GMP production methods. Aristotle University of Thessaloniki Seminar (05/2017)
• International course care and use of laboratory animals (mice, rats, and zebrafish), FELASA accredited course (Ref. No. 051/15)
1.Mechanical stress affects methylation pattern of GNAS isoforms and osteogenic differentiation of hAT-MSCs. Vlaikou AM, Kouroupis D, Sgourou A, Markopoulos GS, Bagli E, Markou M, Papadopoulou Z, Fotsis T, Nakos G, Lekka ME, Syrrou M. Biochim Biophys Acta. 2017 Aug;1864(8):1371-1381. doi:10.1016/j.bbamcr.2017.05.005
2.Medium-term Electrophysiologic Effects of a Cellularized Scaffold Implanted in Rats After Myocardial Infarction. Kolettis TM, Bagli E, Barka E, Kouroupis D, Kontonika M, Vilaeti AD, Markou M, Roumpi M, Maltabe V, La Rocca V, Agathopoulos S, Fotsis T. Cureus. 2018 Jul 10;10(7): e2959. doi:10.7759/cureus.2959
3.Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes. Markou M, Kouroupis D, Badounas F, Katsouras A, Kyrkou A, Fotsis T, Murphy C, Bagli E. Front Bioeng Biotechnol. 2020 Apr 17; 8:278. doi: 10.3389/fbioe.2020.00278
4.“Vascularization in 3D Cell Culture”. Chapter in ‘’ Basic Concepts on 3D Cell Culture’’ book. Markou M, Kouroupis D, Fotsis T, Bagli E, Murphy C. Springer ISBN 978-3-030-66749-8. 2021. https://doi.org/10.1007/978-3-030-66749-8
5. Embryonic Stem Cells Are Devoid of Macropinocytosis a Trafficking Pathway for Activin A in Differentiated Cells. Kostopoulou N, Bellou S, Bagli E, Markou M, Kostaras E, Hyvönen M, Kalaidzidis Y, Papadopoulos A, Chalmantzi V, Kyrkou A, Panopoulou K, Fotsis T & Murphy C. J Cell Sci. 2021 Jul 1;134(13): jcs246892. doi: 10.1242/jcs.246892
6. Translational control in neurovascular brain development. Chalkiadaki K, Statoulla E, Markou M, Bellou S, Bagli E, Fotsis T, Murphy C, Gkogkas C. R Soc Open Sci. 2021 Oct 13;8(10):211088. doi:10.1098/rsos.211088.