Publications
A potential role for the COOH-terminal domain in the lateral packing of type III intermediate filaments. P. D. Kouklis, T. Papamarcaki, A. Merdes, and S. D. Georgatos. (1991) J. Cell Biol. 114:773-786
The “lamin B- fold”. T. Papamarcaki, P. D. Kouklis, T. Kreis, and S. D. Georgatos. (1991) J. Biol. Chem. 266:21247-21251.
Involvement of the consensus sequence motif at coil 2b in the assembly and stability of vimentin filaments. P. D. Kouklis, P. Traub, and S. D. Georgatos. (1992) J. Cell Sci. 102:31-41.
In vitro assembly properties of vimentin mutagenised at the beta-site tail motif. P. D. Kouklis, M. Hatzfeld, M. Brunkener, K. Weber, and S. D. Georgatos. (1993). J. Cell Sci. 106:919-928.
Transient arrest of 3T3 cells in mitosis and inhibition of nuclear lamina reassembly around chromatin induced by an anti- vimentin antibodies. P. D. Kouklis , A. Merdes, T. Papamarcaki, and S. D. Georgatos. (1993) Eur. J. Cell Biol. 62:224-236.
The roles of the rod end and the tail in vimentin IF assembly and IF network formation. M. B. McCormick, P. D. Kouklis, D. Syder, and E. Fuchs. (1993) J. Cell Biol. 122:395-408.
Making a connection: Direct binding between keratin intermediate filaments and desmosomal proteins. P. D. Kouklis, E. Hutton, and E. Fuchs. (1994) J. Cell Biol. 127:1049-1060.
A new type of cytoskeletal protein: Connecting actin microfilaments to intermediate filaments. Y. Yang, J. Dowling, Q.C. Yu, P. D. Kouklis, D. Cleveland, and E. Fuchs. (1996) Cell 86:655-665.
Desmoplakin is required early in development for stabilization of desmosomes and cytoskeletal linkage. G. I. Gallicano*, P. Kouklis*, C. Bauer, M. Yin, V. Vasioukhin, L. Degenstein, and E. Fuchs. (1998) J. Cell Biol. 143:2009-2022 *first co-authors
Increased microvessel permeability and its reversibility in mouse lung in response to VE-cadherin disassembly and reassembly. X. Gao, P. Kouklis, N. Xu, R. D. Minshall, R. Sandoval, S. M. Vogel and A. B. Malik. (2000). Am J Physiol Lung Cell Mol Physiol. 279:L1218-L1225
Ca 2+ signalling and PKCa activate increased endothelial permeability by dissasembly of VE-cadherin junctions. (2001). R. Sandoval, A. B. Malik, R. D. Minshall, P. Kouklis, C. A. Ellis and C. Tiruppathi.
J. Physiol. 533:433-445.
VE-cadherin induced Cdc42 signaling regulates formation of membrane protrusions in endothelial cells. (2003) P. Kouklis, M. Konstantoulaki and A. B. Malik. J. Biol Chem. 278:16230-16236.
Protein Kinase C modifications of VE-cadherin, p120, and b-catenin contribute to endothelial barrier dysregulation induced by thrombin. (2003). M. Konstantoulaki, P. Kouklis and A. B. Malik Am J Physiol Lung Cell Mol Physiol. 285(2):L434-42.
Cdc42 involvement in restoration of endothelial junctional integrity (2004).P. Kouklis, M. Broman, S. Vogel and A. B. Malik. Circulation Research 94:159-166
Cdc42 regulates adherens junction stability and endothelial permeability by inducing alpha-catenin interaction with the vascular endothelial cadherin complex (2006). Broman, M. T., P. Kouklis, et al Circulation Research 98(1): 73-80.
Regulation of Lung Neutrophil Recruitment by VE-cadherin (2006). Orrington-Myers, J., X. P.Gao, P. Kouklis, M. Broman, A. Rahman, A., Vogel,S. and Malik, A. B. Am J Physiol Lung Cell Mol Physiol. 291(4):L764-L771
Ramchandran, R., Mehta, D., Vogel, S. M., Mirza, M. K., Kouklis, P. and Malik, A. B. (2008). Critical role of Cdc42 in mediating endothelial barrier protection in vivo. Am J Physiol Lung Cell Mol Physiol. 295 (2): 363-369
Nikitopoulou, I., Orfanos, SE., Kotanidou, A., Maltabe, V., Manitsopoulos, N., Karras, P., Kouklis, P., Armaganidis, A., Maniatis, NA. (2016) Vascular endothelial-cadherin downregulation as a feature of endothelial transdifferentiation in monocrotaline-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 311(2):L352-63.
Maltabe, VA., Barka, E., Kontonika, M., Florou, D., Kouvara-Pritsouli, M., Roumpi, M., Agathopoulos, S., Kolettis, TM., Kouklis, P. (2016) Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity. Stem Cells Int.;2016:8305624.