"Development of new infrastructure that builds “aptitude” in biomedical research (BIOMED-20)"
Funding Source:
Hellenic Ministry of Development and Investments (ESPA 2014-2020)
Contract Number:
MIS 5047236
Researchers:
A. Magklara
Role:
Participant (Scientific Responsible: Prof. S.Georgatos, University of Ioannina)
Budget:
113.500 € (3.000.000 € total budget)
Duration:
11/2020 - 04/2023
Programme:
Supporting Regional Excellence
Title:
"Understanding pathways of healthy ageing (in health and disease) through integration of high resolution omics data (pathAGE)"
Funding Source:
Hellenic Ministry of Development and Investments (ESPA 2014-2020)
Contract Number:
MIS 5047228
Researchers:
A. Magklara
Role:
Participant (Scientific Responsible: Assoc. Prof. I. Tzoulaki, University of Ioannina)
Budget:
410.300 € (3.000.000 € total budget)
Duration:
11/2020 - 04/2023
Programme:
FORTH SYNERGY GRANT
Title:
"Modelling neurological disorders using graphene-based neurovascular organoids derived from pluripotent human cells"
Funding Source:
Competitive FORTH Inter-Institutional, Interdisciplinary award
Contract Number:
Researchers:
Role:
Budget:
60.000 € Co-ordinator: C. Gkogkas, IMBB-BR, FORTH, Ioannina. Co-PIs: C. Murphy, IMBB-BR, FORTH, Ioannina and G. Deligeorgis, IESL, FORTH, Heraklion, Crete
Duration:
2020-2022
Programme:
Fondation Santé
Title:
"Modelling neurological disorders using human forebrain organoids"
Funding Source:
Fondation Santé, Greece
Contract Number:
Researchers:
C. Gkogkas
Role:
Budget:
€ 50,000
Duration:
2020-2022
Programme:
Competitiveness, Entrepreneurship and Innovation
Title:
"Innovative development of new anticancer drugs with a therapeutic target for the oncoprotein MYC"
Funding Source:
Ministry of Finance, NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 42.500
Duration:
2018-2022
Programme:
National Roadmap for Research Infrastructures
Title:
"BioImaging-GR: The Greek Research Infrastructure for the Imaging and Monitoring of Fundamental Biological Processes"
Funding Source:
Ministry of Education and Religious Affairs, NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible
Budget:
€ 204.500 Euro (for the infrastructure of Ioannina)
Duration:
2018-2022
Programme:
Bilateral and Multilateral R&T Greece-China Co-operation (ESPA 2014-2020)
Title:
"Development of probiotic-enriched food products incorporated in prebiotic matrices (ProBiYo)"
Funding Source:
Hellenic Ministry of Development and Investments (ESPA 2014-2020)
Contract Number:
MIS 5049149
Researchers:
A. Magklara
Role:
Participant (Co-Ordinator: Yiotis)
Budget:
120.000 € (550.000 € total budget)
Duration:
10/2020 - 10/2022
Programme:
Operational Program Competitiveness, Entrepreneurship, and Innovation, under the call RESEARCH – CREATE - INNOVATE
Title:
"Holistic Approach along the production cycle of Stevia Rebaudiana plant cultivated in Greece, via combined application of innovative methods of Precision Agriculture and bitter aftertaste removal techniques (TasteStevia)"
Funding Source:
Hellenic Ministry of Development and Investments (ESPA 2014-2020)
Contract Number:
MIS 5031858
Researchers:
A. Magklara
Role:
Participant (Co-Ordinator: Yiotis)
Budget:
150.000 € (1.000.000 € total budget)
Duration:
09/2018 - 07/2022
Programme:
Human Resource Development, Education and Lifetime Learning. ESPA 2014-2020 co-financing of Greece/European Union
Title:
"Creation of distinct types of Mural Cells by the differentiation of human pluripotent stem cells and their application in vascularised tissue constructs"
Funding Source:
ESPA 2014-2020 co-financing of Greece/European Union
Contract Number:
MIS 5047550
Researchers:
C. Murphy
Role:
Principal investigator
Budget:
(for the team): Budget: 45.500 €
Duration:
2020-2021
Programme:
Hellenic Ministry of Finance and Development & Tourism; Type of Grant: PA 2014-2020/Interreg Greece-Italy/2
Title:
"Integrated Envirinomental Management (2.1); Title: Promoting Silver tourism through valorization of MED-diet and wellbeing routes in the CBC area; Acronym: Silver wellbeing"
Funding Source:
Hellenic Ministry of Finance and Development & Tourism; Type of Grant: PA 2014-2020/Interreg Greece-Italy/2
Contract Number:
5003627
Researchers:
Role:
Budget:
(for the team): Budget: 891.999,12 €. Principal Investigator for IMBB-BR: Theodore FOTSIS; Budget for IMBB-BR: 158.619,25 €
Duration:
2018-2021
Programme:
Reinforcement of Postdoctoral Researchers - 2nd Cycle
Title:
"Study of the molecular mechanism of galectin-1 entry into Weibel Palade bodies and exocytosis, in endothelial cells"
Funding Source:
IKY, Co-financed by Greece and the European Union (European Social Fund-ESF)
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible of the Post-doctoral fellow
Budget:
€ 19,605
Duration:
2019-2021
Programme:
Reinforcement of Postdoctoral Researchers - 2nd Cycle
Title:
"Regulation of stem cell differentiation via endocytosis"
Funding Source:
IKY, Co-financed by Greece and the European Union (European Social Fund-ESF)
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible of the Post-doctoral fellow
Budget:
€ 19,605
Duration:
2019-2021
Programme:
Competitiveness, Entrepreneurship and Innovation
Title:
"Innovative development of new anticancer drugs with a therapeutic target for the oncoprotein MYC"
Funding Source:
Ministry of Finance, NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 42,500 (for our team)
Duration:
2018-2021
Programme:
National Roadmap for Research Infrastructures
Title:
"BioImaging-GR: The Greek Research Infrastructure for the Imaging and Monitoring of Fundamental Biological Processes"
Funding Source:
Ministry of Education and Religious Affairs, NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible for the Ioannina team
Budget:
€ 204,500 Euro (for the infrastructure of Ioannina)
Duration:
2018-2021
Programme:
Internal IMBB Bridging/Supporting Research Grant
Title:
"Investigation of the mechanism of action of the canonical NF-κB signalling pathway in lung carcinogenesis"
Funding Source:
IMBB-FORTH, Ioannina, Greece
Contract Number:
Researchers:
E. Kolettas
Role:
PI
Budget:
10.000 €
Duration:
2020-2021
Programme:
Supporting researchers with an emphasis on young researchers
Title:
"How do mitochondria regulate stress? Lets ask metabolomics"
Funding Source:
Hellenic Ministry of Education, Research and Religious affairs (ESPA 2014-2020)
Contract Number:
Researchers:
M. Filiou
Role:
PI
Budget:
45.546 € (For the lab: 26.500€)
Duration:
2020-2021
Programme:
Hellenic Foundation for Research and Innovation grants
Title:
"The bioenergetic dimension of stress: focus on mitochondria" (ENERGEIA)
"Holistic Approach along the production cycle of Stevia Rebaudiana plant cultivated in Greece, via combined application of innovative methods of Precision Agriculture and bitter aftertaste removal techniques"
Funding Source:
Hellenic Ministry of Finance and Development (ESPA 2014-2020)
Contract Number:
MIS 5031858
Researchers:
A. Magklara
Role:
Participant
Budget:
75.000 € (for the team)
Duration:
09/2018 - 08/2021
Programme:
ARCHERS-FORTH, Stavros Niarchos Foundation
Title:
"Interconnections between metabolism and endocytosis: elucidation of the role of a new interaction between Rab5 and the cytoplasmic thiolase ACAT2"
Action: "Research-Create-Innovate", Operational Programme "Competitiveness, Entrepreneurship and Innovation"
Title:
"Innovative development of new anticancer drugs with a therapeutic target for the oncoprotein MYC"
Funding Source:
Ministry of Finance, NSRF 2014-2020
Contract Number:
MIS5031813
Researchers:
S. Christoforidis
Role:
Partner
Budget:
€ 42,500 (FORTH)
Duration:
2018-2020
Programme:
ΕDΒΜ34 for the "Support of researchers with emphasis on young researchers", Operational Programme "Development of Human Resources, Education and Lifelong Learning"
Title:
"Mechanisms of Differentiation of Stem Cells into Endothelial Cells"
Funding Source:
Ministry of Finance, NSRF 2014-2020
Contract Number:
MIS5004410
Researchers:
S. Christoforidis
Role:
Principal Investigator
Budget:
€ 72,100 (FORTH)
Duration:
2017-2020
Programme:
National Roadmap for Research Infrastructures, Operational Programme "Competitiveness, Entrepreneurship and Innovation"
Title:
"BioImaging-GR: The Greek Research Infrastructure for the Imaging and Monitoring of Fundamental Biological Processes"
Funding Source:
Ministry of Education and Religious Affairs, NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 16,000 (FORTH)
Duration:
2017-2020
Programme:
Siemens Grant, Biology - Biophotonics - Health
Title:
"Modern Technological Approaches and Applications in the Field of Biology, Biophotonics and Health"
Funding Source:
General Secretariat for Research and Technology, GSRT, Greece
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 25,704 (FORTH)
Duration:
2017-2020
Programme:
Competitiveness, Entepreneurship & Innovation
Title:
"Advanced Research Activities in Biomedical Technology and Agri-food; Acronym: ΒΙΤΑΔ. FORTH"
Funding Source:
Hellenic Ministry of Finance and Development; PA 2014-2020/ Competitiveness, Entepreneurship & Innovation
Contract Number:
MIS 5002469
Researchers:
T. Fotsis
Role:
Budget:
for FORTH: 2.319.500 €. Budget for IMBB-BR: 600.000 €; Budget for team:
Duration:
08/09/2017 - 08/09/2020
Programme:
Supporting researchers with an emphasis on young researchers (EDBM34)
Title:
"The role of epigenetic mechanisms of regulation of gene expression in breast cancer heterogeneity - Prospects for targeted therapies"
Funding Source:
Hellenic Ministry of Education, Research and Religious affairs (ESPA 2014-2020)
Contract Number:
MIS 5004375
Researchers:
A. Magklara
Role:
Scientific responsible
Budget:
40.600 €
Duration:
11/2018 - 01/2020
Programme:
Human Resources Development, Education and Lifelong Learning: Strengthening human research potential through doctoral research
Title:
"Molecular mechanisms of asymmetric cell division during stem cell differentiation"
Funding Source:
ΙΚΥ (State Scholarship Foundation); Type of Grant: PA 2014-2020/Human Resources Development, Education and Lifelong Learning: Strengthening human research potential through doctoral research. Thesis Supervisor: Theodore FOTSIS; Ph.D Student: Evangelos DROUGKAS; Host Organisation: University of Ioannina
Contract Number:
SPA00225-10
Researchers:
T. Fotsis
Role:
Budget:
(for the team): 23.391 €
Duration:
01/05/2018 – 21/01/2020
Programme:
Competitiveness, Entepreneurship & Innovation
Title:
"Advanced Research Activities in Biomedical Technology and Agri-food"
Funding Source:
Hellenic Ministry of Finance and Development
Contract Number:
MIS 5002469
Researchers:
A. Magklara
Role:
Participant
Budget:
37.554,98 € (for team)
Duration:
09/2017 - 12/2019
Programme:
National Roadmap for Research Infrastructures, Operational Programme "Competitiveness, Entrepreneurship and Innovation", KRHPIS II
Title:
"Advanced research activities in Biomedical Technology and Agridiet"
Funding Source:
Ministry of Education and Religious Affairs, NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 45,000 (for the team)
Duration:
2016-2019
Programme:
ARCHERS
Title:
"Investigation of canonical NF-κB regulated target genes involved in lung cancer to develop novel potential therapies"
Funding Source:
STAVROS NIARCHOS FOUNDATION
Contract Number:
Researchers:
E. Kolettas
Role:
PI (IMBB-FORTH, Biomedical Research Division)
Budget:
8.400 €
Duration:
2019-2019
Programme:
BIOMEDTECH - Molecular Analysis of Biological Systems and Disease Models
Title:
"Impact of canonical NF-κB signalling, ΙΚΚβ-NFκB p65, on lung carcinogenesis"
Funding Source:
General Secretariat for Research and Technology, GSRT, Greece
Contract Number:
MIS 5002469
Researchers:
E. Kolettas
Role:
IMBB-FORTH, Biomedical Research Division; PI WP4.3
Budget:
580.000 € (Lab: 38.500 €)
Duration:
2017-2019
Programme:
Human Resources Development, Education and Lifelong Learning: Strengthening human research potential through doctoral research
Title:
"Molecular Mechanisms of VEGF in Vasculogenesis and Applications in Regenerative Medicine"
Funding Source:
ΙΚΥ (State Scholarship Foundation); Type of Grant: PA 2014-2020/Human Resources Development, Education and Lifelong Learning: Strengthening human research potential through doctoral research. Thesis Supervisor: Theodore FOTSIS; Ph.D Student: Maria MARKOU; Host Organisation: University of Ioannina
Contract Number:
MIS 5000433
Researchers:
T. Fotsis
Role:
Budget:
(for the team): 29.408 €
Duration:
09/12/2019 – 08/12/2019
Programme:
Research Grants in Biomedicine
Title:
"The role of the histone demethylase LSDl in breast cancer"
Funding Source:
Bodossaki Foundation
Contract Number:
Researchers:
A. Magklara
Role:
Principal Investigator
Budget:
40.000 €
Duration:
06/2018 - 05/2019
Programme:
Biomedical Research Grants
Title:
"Deciphering the role of histone demethylase LSDl in the epigenetic dynamics of breast Cancer Stem Cells"
Funding Source:
Fondation Santé
Contract Number:
Researchers:
A. Magklara
Role:
Principal Investigator
Budget:
40.000 €
Duration:
03/2017 - 02/2019
Programme:
Strengthening the Human Research Potential Through Doctoral Research-2nd Cycle
Title:
"Isolation and characterization of breast cancer stem cells"
Funding Source:
State Scholarships Foundation (IKY) and ESPA 2014-2020
Contract Number:
Researchers:
A. Magklara
Role:
Scientific responsible
Budget:
15.521 € (scholarship to PhD student John Verigos)
Duration:
05/2017 - 12/2018
Programme:
Scholarship Programme for 2nd phase Postgraduate Studies, Operational Programme "Development of Human Resources, Education and Lifelong Learning"
Title:
“Study of spatiotemporal coordination of RabGTPases in regulated exocytosis in endothelial cells”
Funding Source:
Directorate of Scholarships (IKY), NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Supervisor of the recipient of the fellowship
Budget:
€ 12,240 (fellowship)
Duration:
2017-2018
Programme:
Scholarship Programme for 2nd phase Postgraduate Studies, Operational Programme "Development of Human Resources, Education and Lifelong Learning"
Title:
“Spatiotemporal coordination and mechanisms of communication between endocytosis and regulated exocytosis upon signalling by VEGFR2”
Funding Source:
Directorate of Scholarships (IKY), NSRF 2014-2020
Contract Number:
Researchers:
S. Christoforidis
Role:
Supervisor of the recipient of the fellowship
Budget:
€ 12,240 (fellowship)
Duration:
2017-2018
Programme:
ARCHERS
Title:
"Defining canonical NF-κB regulated target genes involved in lung cancer to develop novel biomarkers and potential therapies"
Funding Source:
STAVROS NIARCHOS FOUNDATION
Contract Number:
Ref#SNF0031
Researchers:
E. Kolettas
Role:
PI (IMBB-FORTH, Biomedical Research Division)
Budget:
28.500 €
Duration:
2017-2018
Programme:
Human Resources Development, Education and Lifelong Learning: Strengthening human research potential through doctoral research
Title:
"Targeted Medications: Endocytosis, trafficking and Molecular Mechanism of Action"
Funding Source:
ΙΚΥ (State Scholarship Foundation); Type of Grant: PA 2014-2020/Human Resources Development, Education and Lifelong Learning: Strengthening human research potential through doctoral research. Thesis Supervisor: Theodore FOTSIS; Ph.D Student: Anastasia KOUGIOUMTZI; Host Organisation: University of Ioannina
Contract Number:
MIS 5003404
Researchers:
T. Fotsis
Role:
Budget:
(for the team): 29.408 €
Duration:
15/05/2017 – 15/10/2018
Programme:
ARCHERS: Advancing Young Researchers’ Human Capital in Cutting Edge Technologies in the Preservation of Cultural Heritage and the Tackling of Societal Challenges
Title:
"Study of LSD1 in mammary cancer stem cells"
Funding Source:
Stavros Niarchos Foundation–FORTH Fellowship
Contract Number:
Researchers:
A. Magklara
Role:
Scientific responsible
Budget:
30.838 € (post-doctoral fellowship to Dr. P. Karakaidos)
Duration:
08/2017 - 07/2018
Programme:
The Centre of Membrane Proteins and Receptors (COMPARE)
Title:
"Elucidating Activin A receptor complex trafficking and signalling: link to cell differentiation"
Funding Source:
The Centre of Membrane Proteins and Receptors (COMPARE)
Contract Number:
DLABGBI1270
Researchers:
T. Fotsis
Role:
Budget:
(for the team): £25,000
Duration:
2016-2017
Programme:
Research program for the development of research institutes
Title:
"Kripis I: Biology, Biophotonics, and Health: Modern technological approaches and applications in the filed of Biology, Photonics and Health"
Funding Source:
GSRT. Research program for the development of research institutes
Contract Number:
MIS 448301
Researchers:
T. Fotsis
Role:
Budget:
(for the team): Budget for IMBB-BR:.300,000 €; Budget for Murphy 6,000€
Duration:
2015-2017
Programme:
Excellence - IKY Siemens
Title:
"Coorrdination between metabolism, endocytosis and signalling: The role of the interaction between the metabolic enzyme ACAT2 and the GTPase Rab5"
Funding Source:
IKY-Siemens
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible
Budget:
€ 49,300
Duration:
2015-2017
Programme:
BIOLOGY, BIOPHOTONICS and HEALTH
Title:
"Modern technological approaches & applications in the field of Biology, Photonics & Health‘ WP3.1: 'Biological-Experimental Models & Systems Biology'; Τitle: ‘The role of IKK/NF-κB signalling pathways on DNA damage and cancer"
Funding Source:
General Secretariat For Research and Technology (Programmatic Agreements between Research Centres-GSRT 2015-2017, in the framework of the Hellenic Republic-Siemens agreement)
Contract Number:
5957/22-12-2016
Researchers:
E. Kolettas
Role:
Participant; Coordinator: IMBB-FORTH, Biomedical Research Division
Budget:
8.000 €
Duration:
2015-2017
Programme:
RESEARCH GRANTS IN BIOMEDICAL SCIENCES
Title:
"Impact of IKKa and IKKb signalling on the control of E2F-target genes during K-Ras oncogene-mediated senescence of human fibroblasts"
Funding Source:
FONDATION SANTÉ
Contract Number:
Researchers:
E. Kolettas
Role:
PI (IMBB-FORTH, Biomedical Research Division)
Budget:
40.000 €
Duration:
2014-2016
Programme:
Research Grants in Biomedicine
Title:
"The role of the histone demethylase LSDl in breast cancer"
Funding Source:
Bodossaki Foundation
Contract Number:
Researchers:
A. Magklara
Role:
Principal Investigator
Budget:
40.000 €
Duration:
12/2015 - 11/2016
Programme:
Marie Curie Actions-Career Reintegration Grant
Title:
"The Epigenome of Breast Cancer Stem Cells"
Funding Source:
European Union (FP7-PEOPLE-2011-CIG)
Contract Number:
303519
Researchers:
A. Magklara
Role:
Principal Investigator
Budget:
100.000 €
Duration:
03/2012 - 02/2016
Programme:
National Strategic Reference Framework (GSRT)
Title:
"StemCycle. Stem Cycle Variations: Comparing the Stem Cell and Cancer Cell Life Cycles"
Funding Source:
General Secretariat for Research and Technology, GSRT, Greece
Contract Number:
Researchers:
C. Murphy, T. Fotsis
Role:
Responsible for IMBB-BR: Carol Murphy
Budget:
€ 600.000
Duration:
2011-2015
Programme:
National Strategic Reference Framework (NSRF)
Title:
"Remodeling Diabetic and Ischemic Retinal Vasculature Using Progenitor Stem Cells"
Funding Source:
General Secretariat for Research and Technology, GSRT, Greece
Contract Number:
LS7 (2012)
Researchers:
E. Bagli, C. Murphy, T. Fotsis
Role:
Scientific responsible Carol Murphy
Budget:
€ 150.000
Duration:
2011-2015
Programme:
Cross-Border Cooperation within the European Neighbourhood and Partnership Instrument (ENPI)
Title:
"Mobility, exchanges, training and professionalism of young experts from the Mediterranean basin in the field of safety evaluation and risk assessment of botanicals. "BRAMA"
Funding Source:
European Regional Development Fund (ERDF)
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 15.000 (for our team)
Duration:
2012-2015
Programme:
Excellence (Aristeia)
Title:
"Endocytosis, regulated secretion, and signalling in endothelial cells: Coordination, molecular mechanisms and implications in blood vessel diseases. Acronym: SecrEndo"
Funding Source:
General secretary of Research and Technology, Ministry of Education
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible
Budget:
€ 177,000
Duration:
2014-2015
Programme:
Kripis
Title:
"Basic mechanisms of differentiation of stem cells"
Funding Source:
General secretary of Research and Technology, Ministry of Education
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 45,000 (for our team)
Duration:
2013-2015
Programme:
New Knowledge
Title:
"Thrombosis and Inflammation: The diagnostic and therapeutic significance of the secretory mechanism of endothelial cells"
Funding Source:
Operational Programme, Periphery of Epirus
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible
Budget:
€ 150,000
Duration:
2013-2015
Programme:
Cooperation/Large Scale Cooperative Projects
Title:
"PIK3CA Oncogenic Mutations in Breast and Colon Cancers: Development of Targeted Anticancer Drugs and Diagnostics.Acronym: POM"
Funding Source:
National Strategic Reference Framework (NSRF) 2007-2013, General secretary of Research and Technology, Ministry of Education
Contract Number:
Researchers:
S. Christoforidis
Role:
Participant
Budget:
€ 63,000 (for our team)
Duration:
2011-2015
Programme:
STATE (IKY) FELLOWSHIPS OF EXCELLENCE FOR POSTDOCTORAL RESEARCH IN GREECE - SIEMENS
Title:
"Investigation of the role of IKK-mediated NF-kB signalling on the regulation of E2F-target cell cycle effectors during K-Ras-induced senescence of human fibroblasts"
Funding Source:
State Scholarships Foundation
Contract Number:
Researchers:
E. Kolettas
Role:
PI, Supervisor of a Postdoctoral Fellow (UoI)
Budget:
39.000 €
Duration:
2014-2015
Programme:
THALIS (GenAge), ESPA
Title:
"Senescence and Longevity - Interaction of Genetic and Environmental factors: The role of genetic and environmental factors in aging and longevity"
Funding Source:
Hellenic Ministry of Education/EU
Contract Number:
380228
Researchers:
E. Kolettas
Role:
Participant (IMBB-FORTH); Coordinator: G. Garinis, IMBB-FORTH, Crete
Budget:
600.000 € (Lab: 21.600 € to fund a postdoc researcher for 18 months)
Duration:
2012-2015
Programme:
THALIS (CancerTFs), ESPA
Title:
"Defining novel mechanisms whereby IKK dependent-NF-κB activation impacts on the control of E2F-target genes in normal and cancer cells‘ Secondary Title: 'Defining novel mechanisms whereby IKK-dependent NF-κB activation impacts on the control of E2F-target genes during lung cancer development and progression"
Funding Source:
Hellenic Ministry of Education/EU
Contract Number:
379435
Researchers:
E. Kolettas
Role:
Coordinator (UoI); Members (16): University of Ioannina (4 members); Biomedical Research Foundation, Academy of Athens (4 members); University of Athens Medical School (3 members); Democritus University of Thrace, Alexandroupolis (3 members); K. B. Marcu, Stony Brook University, USA
Budget:
600.000 €
Duration:
2012-2015
Programme:
National Strategic Reference Framework (NSRF)
Title:
"Treating the Rupture of Anterior Cruciate Ligament: Regeneration using Stem Cells and Tissue Engineering"
Funding Source:
National Strategic Reference Framework (NSRF) 2007-2013 – Region of Epirus
Contract Number:
346955
Researchers:
T. Fotsis
Role:
Budget:
(for the team): 147.922,25 €
Duration:
01/08/2011 – 31/05/2014
Programme:
Cooperation/Large Scale Cooperative Projects
Title:
"PIK3CA Oncogenic Mutations in Breast and Colon Cancers: Development of Targeted Anticancer Drugs and Diagnostics. Acronym: POM"
Funding Source:
National Strategic Reference Framework (NSRF) 2007-2013 (GSRT)
Contract Number:
09SYN-11-675
Researchers:
A. Efstratiadis, T. Fotsis, C. Murphy, S. Christoforidis
Role:
Principal investigator
Budget:
€ 1.962.900 (189.000 for the Ioannina team)
Duration:
2007-2013
Programme:
Cooperation/Large Scale Cooperative Projects
Title:
"Mechanisms of Induced Pluripotency: From Transcriptional Noise to Stem Cell Therapies. Acronym: NoisePlus"
Funding Source:
National Strategic Reference Framework (NSRF) 2007-2013 (GSRT)
Contract Number:
09SYN-21-969
Researchers:
D. Thanos, S. Georgatos, T. Fotsis, C. Murphy, S. Christoforidis
Role:
Scientific responsible
Budget:
€ 1.680.000 (444.500 for the Ioannina team)
Duration:
2007-2013
Programme:
Education and Lifelong Learning program "Supporting Postdoctoral Researchers"
Title:
"Bone Regeneration Using Keratin-Based Biomaterials And Mesenchymal Stem Cells. Acronym: Postdoctoral"
Funding Source:
National Strategic Reference Framework (NSRF) 2007-2013 (GSRT)
Contract Number:
346955
Researchers:
T. Teli, T. Fotsis, C. Murphy, S. Christoforidis
Role:
Scientific responsible
Budget:
€ 150.000
Duration:
2007-2013
Programme:
Hraklitos II
Title:
"The role of VEGFR2 compartmentalization in VEGF signalling"
Funding Source:
Greek Ministry of Education
Contract Number:
Researchers:
S. Christoforidis
Role:
Scientific responsible
Budget:
€ 45,000
Duration:
2010-2012
Programme:
Investigation of the role of Rho GTPases
Title:
"Investigation of the role of Rho GTPases in the regulation of the genomic and non-genomic responses of cells to cytokines"
Funding Source:
General Secretariat for Research and Technology, GSRT, Greece
Contract Number:
PENED 2003/03ED688
Researchers:
T. Fotsis
Role:
Budget:
(for the team): Total Budget 180,000 €, for IMBB-BR 44,625 €
Duration:
2006-2010
Programme:
FP6 Integrated Project οf EC
Title:
"Tracking the Endocytic Routes of Polypeptide Growth Factor Receptor Complexes and their Modulatory Role on Signalling (EndoTrack)"
Funding Source:
FP6 Integrated Project οf EC
Contract Number:
LSHG-CT-2006-019050
Researchers:
M. Zerial, C. Murphy, T. Fotsis, S. Christoforidis
Role:
Senior investigator and Co-applicant
Budget:
€ 10.864.508 (1.045.758 for the Ioannina team)
Duration:
2006-2010
Programme:
FP6 Integrated Project οf EC
Title:
"Pulmonary Hypertension: Functional Genomics and Therapy of Lung Vascular Remodelling (Pulmotension)"
Funding Source:
FP6 Integrated Project οf EC
Contract Number:
LSHM-CT-2006-018725
Researchers:
W. Seeger, S. Christoforidis, T. Fotsis, C. Murphy
Role:
Senior investigator and Co-applicant
Budget:
€ 11.400.00 (360.068 for the Ioannina team)
Duration:
2006-2010
Programme:
PENED 2003
Title:
"Molecular mechanisms of signal transduction, cytoskeleton and secretion during endothelial thrombosis and inflammation"
Funding Source:
Ministry of Development – Science and Technology
Contract Number:
Researchers:
P. Kouklis
Role:
Budget:
€ 199.080
Duration:
2006-2009
Programme:
PENED
Title:
"Inter-relationships between molecular mechanisms of signal transduction, cytoskeleton and secretion in thrombosis and inflammation"
Funding Source:
General secretary of Research and Technology, Ministry of Education
Contract Number:
Researchers:
P. Kouklis
Role:
Participant
Budget:
€ 66,360 (for our team)
Duration:
2006-2009
Programme:
PENED 2003
Title:
"Molecular mechanisms involved in H2O2 and TNFα-induced apoptosis of tumour cells"
Funding Source:
General Secretariat of Research and Technology (GSRT), Hellenic Ministry of Development
Contract Number:
2055
Researchers:
E. Kolettas
Role:
PI (UoI)
Budget:
180.000 € (Lab: 60.000 €)
Duration:
2006-2009
Programme:
Bodosakis Foundation
Title:
"Bodosakis Foundation"
Funding Source:
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 40.000
Duration:
2008
Programme:
Marie Curie Re-Integration Award
Title:
"Regulation of endothelial barrier properties through activation of Rho family GTPases"
Funding Source:
EU
Contract Number:
Researchers:
P. Kouklis
Role:
Budget:
€ 80.000
Duration:
2005-2008
Programme:
PENED 2003
Title:
"Novel biological models for the study of gene regulation and epigenetic control"
Funding Source:
GSRT
Contract Number:
Researchers:
T. Agalioti
Role:
Budget:
€ 178.740 (€ 23.000 for Politou team)
Duration:
2006-2008
Programme:
PENED 2003
Title:
"Modeling the histone code: Theoretical simulation and biophysical analysis"
Funding Source:
GSRT
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 199.088 (€ 40.000 for Politou team)
Duration:
2006-2008
Programme:
EPEAEK Pythagoras II
Title:
"The role of chromatin remodeling factors in the apoptotic response to chemotherapy"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
T. Papamarcaki
Role:
Budget:
€ 50.000 (€ 16.500 for Politou team)
Duration:
2005-2008
Programme:
EPEAEK Pythagoras II
Title:
"Nuclear proteins-Histone chaperones: Structural characterization and functional role in chromatin assembly"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 40.000 (€ 13.000 for Politou team)
Duration:
2005-2008
Programme:
EPEAEK Pythagoras II
Title:
"Theoretical simulations and experimental study of the histone code"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
A. Politou
Role:
Principal Investigator
Budget:
€ 42.000
Duration:
2005-2008
Programme:
PENED 2003/03EΔ688, GSRT
Title:
"Investigation of the role of Rho GTPases in the regulation of the genomic and non-genomic responses of cells to cytokines"
Funding Source:
PENED 2003/03EΔ688, GSRT
Contract Number:
Researchers:
C. Stournaras, C. Muprhy, T. Fotsis
Role:
Senior investigator and Co-applicant
Budget:
€ 180.000 (44.625 for the Ioannina team)
Duration:
2006-2008
Programme:
PENED 2003/01EΔ562, GSRT
Title:
"Functional oncogenomics: Mass sclae analysis of the gene function as a novel tool for the diagnosis and treatment of colon cancer"
Funding Source:
PENED 2003/01EΔ562, GSRT
Contract Number:
Researchers:
A. Pintzas, T. Fotsis, C. Murphy
Role:
Principal investigator
Budget:
€ 235.000 (44.000 for the Ioannina team)
Duration:
2006-2008
Programme:
Pythagoras II
Title:
"The role of lipid rafts and caveolae in thrombosis and angiogenesis"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
T. Fotsis, C. Murphy, S. Christoforidis
Role:
Principal investigator
Budget:
€ 50.000
Duration:
2005-2008
Programme:
Pythagoras II
Title:
"Histone Chaperones: Structural characterisation and functional role in chromatin organisation"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
S. Georgatos
Role:
Principal Investigator
Budget:
€ 40.000
Duration:
2005-2008
Programme:
Pythagoras II
Title:
"The role of chromatin structure in the apoptotic response of tumor cells to chemotherapeutic drugs"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
T. Papamarcaki
Role:
Project Manager
Budget:
€ 50.000
Duration:
2005-2008
Programme:
PYTHAGORAS II
Title:
"Mechanisms of action of the transcription factors E2F1 and NF-κB related to cellular senescence and apoptosis of human diploid fibroblasts"
Funding Source:
Hellenic Ministry of Education/EU
Contract Number:
61/1887
Researchers:
E. Kolettas
Role:
PI (UoI)
Budget:
50.000 €
Duration:
2005-2008
Programme:
ARCHIMIDES II
Title:
"Studies on the antioxidant properties and mechanism of action of components of Oregano vulgare L. spp. Hirtum in vitro and in vivo"
Funding Source:
Hellenic Ministry of Education/EU
Contract Number:
9 (11)
Researchers:
E. Kolettas
Role:
PI (UoI)
Budget:
50.531 €
Duration:
2005-2008
Programme:
Onassis Foundation
Title:
"Onassis Foundation"
Funding Source:
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 40.000
Duration:
2007
Programme:
Program of scientific collaboration between Greece and Poland
Title:
"Theoretical and experimental investigation of the structure and dynamics of proteins participating in chromatin remodelling"
Funding Source:
Program of scientific collaboration between Greece and Poland
Contract Number:
Researchers:
A. Politou
Role:
Principal Investigator
Budget:
€ 11.740
Duration:
2006-2007
Programme:
IKYDA
Title:
"Molecular/structural characterization of LBR"
Funding Source:
IKY, Greece and DAD, Germany
Contract Number:
Researchers:
A. Politou
Role:
Principal Investigator
Budget:
€ 10.000
Duration:
2005-2007
Programme:
EPEAEK Herakleitos
Title:
"Structural/Functional characterization of chromodomains"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
A. Politou
Role:
Principal Investigator
Budget:
€ 33.574
Duration:
2004-2007
Programme:
Heracleitos
Title:
"Gene regulation by the angiogenic factor VEGF in endothelial cells"
Funding Source:
Ministry of Education
Contract Number:
Researchers:
T. Fotsis
Role:
Principal investigator
Budget:
€ 34.011
Duration:
2004-2007
Programme:
PENED 2001/01EΔ585, GSRT
Title:
"Signal transduction and intracellular membrane traficking in endothelial cell"
Funding Source:
PENED 2001/01EΔ585, GSRT
Contract Number:
Researchers:
T. Fotsis, C. Murphy, S. Christoforidis
Role:
Principal investigator
Budget:
€ 132.062
Duration:
2003-2007
Programme:
Pythagoras I
Title:
"The role of Aherens Juctions in endothelial differentiation of embryonic Stem Cells"
Funding Source:
EPEAEK (Greek Ministry of Education)
Contract Number:
Researchers:
P. Kouklis
Role:
Budget:
€ 85.000
Duration:
2004-2006
Programme:
EPAN
Title:
"A novel anti-platelet therapeutic approach in acute coronary syndromes: Combined peptide inhibitors of the platelet integrin αIIb/β3-mediated signaling for nasal and intravenous administration"
Funding Source:
GSRT
Contract Number:
Researchers:
D. Sideris
Role:
Budget:
€ 380.000 (€ 21.000 for Politou team)
Duration:
2003-2006
Programme:
BILATERAL SCIENTIFIC AGREEMENT BETWEEN GREECE-CYPRUS
Title:
"Mechanism of action of 2-methoxyestradiol on human T leukaemic cells: The role of the anti-apoptotic gene Bcl-2 and of the transcription factor NF-κB"
Funding Source:
General Secretariat of Research and Technology (GSRT), Hellenic Ministry of Development
Contract Number:
1722
Researchers:
E. Kolettas
Role:
PI (Greece): E. Kolettas, UoI; PI (Cyprus): A. Constantinou, Biological Sciences Dept., University of Cyprus
Budget:
11.400 € (each)
Duration:
2004-2006
Programme:
Heracleitos
Title:
"Oncogenic stress on human cells: The effects of oncogenic stress on cell proliferation, senescence, apoptosis and neoplastic transformation"
Funding Source:
Hellenic Ministry of Education/EU
Contract Number:
11729
Researchers:
E. Kolettas
Role:
PI, Supervisor of PhD student (University of Ioannina; UoI)
Budget:
33.369 €
Duration:
2004-2006
Programme:
Pythagoras II
Title:
"Pythagoras II"
Funding Source:
Ministry of Education (EPEAEK)
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 42.000
Duration:
2005
Programme:
Pythagoras II
Title:
"Pythagoras II"
Funding Source:
Ministry of Education (EPEAEK)
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 40.000
Duration:
2005
Programme:
PENED2003
Title:
"PENED2003"
Funding Source:
GSRT
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 199.088
Duration:
2005
Programme:
PENED2003
Title:
"PENED2003"
Funding Source:
GSRT
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 178.740
Duration:
2005
Programme:
Human Networks, GSRT
Title:
"Applications of photonic microscopy in biomedical research and diagnosis"
Funding Source:
Human Networks, GSRT
Contract Number:
Researchers:
Ch. Boleti, C. Murphy
Role:
Principal investigator
Budget:
€ 180.000 (37.153 for the Ioannina team)
Duration:
2004-2005
Programme:
EMBO Young Investigator program
Title:
"The role of endocytosis and secretion in the antithrombotic function of Endothelial Cells"
Funding Source:
EMBO
Contract Number:
Researchers:
S. Christoforidis
Role:
Principal Investigator
Budget:
€ 55,000
Duration:
2002-2005
Programme:
PENED 2001
Title:
"Signal transduction and intracellular membrane traficking in endothelial cell"
Funding Source:
General secretary of Research and Technology, Ministry of Education
Contract Number:
Researchers:
T. Fotsis
Role:
Participant
Budget:
€ 44,021 (for our team)
Duration:
2002-2005
Programme:
Herakleitos
Title:
"Herakleitos"
Funding Source:
Ministry of Education (EPEAEK)
Contract Number:
Researchers:
S. Georgatos
Role:
Budget:
€ 38.000
Duration:
2004
Programme:
Scientific exchange program
Title:
"Molecular/structural characterization of the interactions between chromodomains and histone tails"
