Publications

Michaelidis, T. M., G. Tzimagiorgis, N. Moschonas, and J. Papamatheakis. (1993). The human glutamate dehydrogenase gene family: gene organization and structural characterization. Genomics 16, 150-160.

Tsiotra, C. P., D. Karagogeos, K. Theodorakis, T. M. Michaelidis, W. S. Modi, J. A. Furley, T. M. Jessell, and J. Papamatheakis. (1993). Isolation of the cDNA and chromosomal localization of the gene (TAX1) encoding the human axonal glycoprotein TAG-1. Genomics 18, 562-567.

Shashidharan, P., T. M. Michaelidis, N. K. Robakis, A. Kretsovali, J. Papamatheakis, and A. Plaitakis. (1994). Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. J. Biol. Chem. 269, 16971-16976.

Tzimagiorgis, G., T. M. Michaelidis, D. Lindholm, and H. Thoenen. (1996). Introduction of the negative selection marker into replacement vectors by a single ligation step. Nucleic Acids Res. 24, 3476-3477.

Ohga, Y., U. Zirrgiebel, S. Hamnér, T. M. Michaelidis, J. Cooper, H. Thoenen, and D. Lindholm. (1996). Cell density increases Bcl-2 and Bcl-x expression in addition to survival of cultured cerebellar granule neurons. Neuroscience 73, 913-917.

Michaelidis, T. M., M. Sendtner, J. D. Cooper, M. Airaksinen, B. Holtmann, M. Meyer, and H. Thoenen. (1996). Inactivation of the bcl-2 gene results in progressive degeneration of motoneurons, sensory and sympathetic neurons during early postnatal development. Neuron 17, 75-89.

Frade, J. M. and T. M. Michaelidis. (1997). Origin of eukaryotic programmed cell death: A consequence of aerobic metabolism? Bioessays 19, 827-832.

Boot-Handford, R. P., T. M. Michaelidis, M. C. Hillarby, A. Zambelli, J. Denton, J. A. Hoyland, A. J. Freemont, M. E. Grant, and G. A. Wallis. (1998). The bcl-2 knockout mouse exhibits marked changes in osteoblast phenotype and collagen deposition in bone as well as a mild growth plate phenotype. Int. J. Exp. Pathology 79, 329-335.

Heix, J., A., Vente, R. Voit, A. Budde, T. M. Michaelidis, and I. Grummt. (1998). Mitotic silencing of rRNA synthesis: Inactivation of the promoter selectivity factor SL1 by cdc2/cyclin B-mediated phosphorylation. EMBO J. 17, 7373-7381.

Cellerino, A., T. M. Michaelidis, J. J. Barski, M. Baehr, H. Thoenen, and M. Meyer. (1999). Retinal ganglion cell loss after the period of naturally occurring cell death in bcl-2-/- mice. Neuroreport 10, 1091-1095.

Hata R., F. Gillardon, T. M. Michaelidis, and K.-A. Hossmann. (1999). Targeted disruption of the bcl-2 gene in mice exacerbates focal ischemic brain injury. Metabolic Brain Disease 14, 117-124.
Gillardon, F., I. Moll, M. Meyer, and T. M. Michaelidis. (1999). Alterations in cell death and cell cycle progression in the UV-irradiated epidermis of bcl-2-deficient mice. Cell Death Differ. 6, 55-60.

Almeida, O. F. X., G. L. Condé, C. Crochemore, B. A. Demeneix, D. Fischer, A. H. S. Hassan, M. Meyer, F. Holsboer, and T. M. Michaelidis. (2000). Subtle shifts in the ratio between pro- and anti-apoptotic molecules following activation of corticosteroid receptors decide neuronal fate. FASEB J. 14, 779-790.

Post A., M. Rücker, F. Ohl, M. Uhr, F. Holsboer, O. F. X. Almeida, and T. M. Michaelidis. (2002). Mechanisms underlying the protective potential of -tocopherol (vitamin E) against haloperidol-associated neurotoxicity. Neuropsychopharmacology 26, 397-407.

Crochemore, C. T. M. Michaelidis, D. Fischer, J.-Ph. Loeffler, and O. F. X. Almeida. (2002). Enhancement of p53 activity and inhibition of neural cell proliferation by activated glucocorticoid receptors. FASEB J. 16, 761-770.

Michaelidis, T. M., and I. Grummt. (2002). Mechanism of inhibition of RNA polymerase I transcription by DNA-dependent protein kinase. Biol. Chem. 383, 1683-1690.

Tirard, M., J. Jasbinsek, O. F. X., Almeida and T. M. Michaelidis (2004). The manifold actions of PIAS proteins on the transcriptional activity of mineralocorticoid and glucocorticoid receptors in neural cells. J. Mol. Endocrinology, 32, 825-841.

Tirard, M., Almeida, O. F., Hutzler, P., Melchior, F. and T. M. Michaelidis (2007). Sumoylation and proteasomal activity determine the transactivation properties of the mineralocorticoid receptor. Mol. Cell. Endocrinol. 268, 20-29.

Apostolova, G., Dorn, R., Ka, S., Hallbook, F., Lundeberg, J., Liser, K., Hakim, V., Brodski, C., Michaelidis, T. M., and Dechant, G. (2007). Neurotransmitter phenotype-specific expression changes in developing sympathetic neurons. Mol. Cell. Neurosci. 35, 397-408.

Sotiropoulos, I., Catania, C., Riedemann, T., Fry, J. P., Breen, K. C., Michaelidis, T. M., and Almeida O. F. X. (2008) Glucocorticoids trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau. J Neurochem. 107, 385-397.

Michaelidis, T. M. and Lie, D. C. (2008) Wnt signaling and neural stem cells: caught in the Wnt web. Cell Tissue Res. 331, 193-210.  

Mu, LF., Berti L., Masserdotti, G., Covic, M., Michaelidis, T.M., Doberauer, K., Merz, K., Rehfeld, F., Haslinger, A., Wegner, M., Sock, E., Lefebvre, V., Couillard-Despres, S., Aigner, L., Berninger, B., Lie, C.D. (2012) “SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.” JOURNAL OF NEUROSCIENCE, 32(9): 3067-3080.